产品
编 号:F758398
分子式:C18H22N2O3S
分子量:346.44
产品类型
结构图
CAS No: 474099-18-8
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产品详情
生物活性:
Antibacterial agent 121 (Compound 10) is an antibacterial agent. Antibacterial agent 121 shows anti-mycobacterial and anti-inflammatory activities and can be used in Tuberculosis (TB) research.
体外研究:
Antibacterial agent 121 (0.2-200 μM; 24 h) inhibits M. tuberculosis H37Rv growth in bacterial culture.Antibacterial agent 121 (0-200 μM; 24 h) inhibits NO production in LPS-stimulated RAW 264.7 cell cultures with an IC50 value of 4.1 μM.Antibacterial agent 121 (6.25-200 μM, 24 h) inhibits TNF-α and IL-1β production in LPS-stimulated macrophages.Antibacterial agent 121 (25-100 μM, 4 d) inhibits M. tuberculosis M299 with an MIC50 value of 24.8 μM.