产品
编 号:F758285
分子式:C26H47NO3
分子量:421.66
产品类型
结构图
CAS No: 444914-19-6
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产品详情
生物活性:
Lepadin E is a significantly cytotoxic ferroptosis inducer that induces iron death through the classical p53-SLC7A11-GPX4 pathway. Lepadin E promoted p53 expression, decreases SLC7A11 and GPX4 levels, and leads to increased ROS and lipid peroxide production, and upregulated ACSL4 expression, thus causes cell death. Lepadin E has significant antitumor effect.
体内研究:
Lepadin E