产品
编 号:F082261
分子式:C31H52N4O7
分子量:592.77
产品类型
结构图
CAS No: 1226851-11-1
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产品详情
生物活性:
LCL521 is an acid ceramidase (ACDase) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase (ASMase).
体外研究:
LCL521 (1 μM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 μM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 μM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells.