产品
编 号:F757847
分子式:C20H25N7OS
分子量:411.52
产品类型
结构图
CAS No: 372495-52-8
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产品详情
生物活性:
UNC10201652 is a potent Loop 1 (L1)-specific gut bacterial β-glucuronidase (GUSs) inhibitor with an IC50 value of 0.117 μM for E. coli GUS. UNC10201652 can block SN-38 glucuronide (HY-126373) processing only in individuals whose fecal gut microbiota is highly abundant in L1 GUS enzymes.
体外研究:
UNC10201652 exhibits potently inhibitory activity against wild type E. coli with an EC50 of 74±7 nM.