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编 号：F757747
分子式：C18H21N5O4
分子量：371.39
分子式：C18H21N5O4
分子量：371.39
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CAS No: 35940-03-5
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生物活性：
Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection.
体外研究：
Antiviral agent 23 (0-100 μM) inhibits CVA21 and EV68 replication in HeLa cells with EC50 values of 36.4 and 8.9 μM, respectively.Antiviral agent 23 (100 μM) inhibits the enzymatic activity of METTL3/METTL14 of 74.45%.Antiviral agent 23 (0-100 μM) shows antiviral effect to EV71 and inhibits the replication of the EV71 strain BrCr in RD cells with an EC50 value of 94 nM.
Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection.
体外研究：
Antiviral agent 23 (0-100 μM) inhibits CVA21 and EV68 replication in HeLa cells with EC50 values of 36.4 and 8.9 μM, respectively.Antiviral agent 23 (100 μM) inhibits the enzymatic activity of METTL3/METTL14 of 74.45%.Antiviral agent 23 (0-100 μM) shows antiviral effect to EV71 and inhibits the replication of the EV71 strain BrCr in RD cells with an EC50 value of 94 nM.
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