产品
编 号:F757442
分子式:C13H15BrCl2N2O4S
分子量:446.14
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10mM*1mL in DMSO
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1mg
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5mg
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10mg
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25mg
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生物活性:
WNK1-IN-1 is a selective inhibitor of WNK1 with an IC50 value of 1.6 μM. WNK1-IN-1 inhibits OSR1 phosphorylation with an IC50 value of 4.3 μM. WNK1-IN-1 can be used for the research of blood pressure regulation and cancer.

体外研究:
WNK1-IN-1 (0-1000 μM; 30 min) shows high potency to WNK1 with an IC50 value of 1.6 μM.WNK1-IN-1 (0.2-12.5 μM; 24 h) inhibits endogenous OSR1 phosphorylation with an IC50 value of 4.3 μM in MDAMB231 breast-cancer cells.WNK1-IN-1 (0-100 mM) is 10-fold more potent to WNK1 than WNK3 in Kinase-Glo assay.
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