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编 号:F757441
分子式:C20H16BrNO5S
分子量:462.31
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10mM*1mL in DMSO
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5mg
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10mg
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25mg
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50mg
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生物活性:
EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus)-related cancer research.

体外研究:
EBNA1-IN-SC7 (compound SC7) (5 μM) can completely block transcriptional activation of EBNA1 and show a 60% inhibition of Zta (EBV-encoded b-zip DNA binding protein) trans-activation in HEK293T cells.EBNA1-IN-SC7 (compound SC7) (10 μM, 6 days) has no significant effect on EBV genome copy number of Raji Burkitt lymphoma cells.
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