产品
编 号:F757290
分子式:C89H153N33O22
分子量:2037.4
产品类型
结构图
CAS No: 309247-48-1
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产品详情
生物活性:
Protein Kinase C (19-35) Peptide is the PKC pseudosubstrate inhibitor/region. Protein Kinase C (19-35) Peptide possibly blocks the substrate-binding site in its kinase domain, makes the cytoplasmic form of PKC inactive.
体外研究:
Amino acids equivalent to residues 19-36 and 19-29 of PKC-β can bound to phospholipid vesicles.Atypical zeta protein kinase C in the signaling pathway leading to chemoattractant-triggered actin assembly, integrin-dependent adhesion of blood leukocytes to vascular endothelium. Synthetic myristoylated peptides with Protein Kinase C (19-35) Peptide, the endogenous zeta protein kinase C pseudosubstrate region, block agonist-induced adhesion to fibrinogen, chemotaxis and F-actin accumulation.