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编 号:F757087
分子式:C18H23N3O4S
分子量:377.46
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结构图
CAS No: 2945983-00-4
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TS-IN-2 (compound 17) is a thymidylate synthase (TS) inhibitor with an IC50 of 0.81 μM. TS-IN-2 induces cancer cell apoptosis and cell cycle arrest in S phase, and also inhibit DNA synthesis, resulting in DNA damage.