产品
编 号：F757050
分子式：C22H17N5O3S
分子量：431.47
分子式：C22H17N5O3S
分子量：431.47
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CAS No: 2938990-92-0
产品详情
生物活性：
KDM1/CDK1-IN-1 (compound 4) is a potent KDM1 and CDK1 inhibitor, with IC50 values of 0.096 and 0.078 μM, respectively.KDM1/CDK1-IN-1 induces cell cycle arrest at G2/M phase and apoptosis in HOP-92 cells. KDM1/CDK1-IN-1 exhibits potent cytotoxic activity against the CCRF-CEM, HOP-92 and Hep-G2 cells, with IC50 values of 16.34, 3.45 and 7.79 μM, respectively.
体外研究：
KDM1/CDK1-IN-1 (compound 4) induces apoptosis by the activation of Caspase-3.
KDM1/CDK1-IN-1 (compound 4) is a potent KDM1 and CDK1 inhibitor, with IC50 values of 0.096 and 0.078 μM, respectively.KDM1/CDK1-IN-1 induces cell cycle arrest at G2/M phase and apoptosis in HOP-92 cells. KDM1/CDK1-IN-1 exhibits potent cytotoxic activity against the CCRF-CEM, HOP-92 and Hep-G2 cells, with IC50 values of 16.34, 3.45 and 7.79 μM, respectively.
体外研究：
KDM1/CDK1-IN-1 (compound 4) induces apoptosis by the activation of Caspase-3.
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