产品
编 号：F081271
分子式：C165H261N51O55S2
分子量：3903.28
分子式：C165H261N51O55S2
分子量：3903.28
产品类型
规格
价格
是否有货
500μg
询价
询价
1mg
询价
询价
结构图
CAS No: 122384-88-7
产品详情
生物活性：
Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent.
体内研究：
Amylin, amide, human (400 μg peptide /kg body weight) is injected by subcutaneous route in separated groups of swiss male mice. A typical PK curve for the free amylin is observed, with a half-time of 23 min.Animal Model:Swiss male mice (8 weeks old)
Dosage:400 μg peptide /kg body weight (Pharmacokinetic Analysis)
Administration:Subcutaneous route; 24 hours
Result:Half-time of 23 min.
体外研究：
MCF-7 cells endogenously express human amylin receptor CTR1 and CTR2. Stimulation of the receptor with Amylin, amide, human results in the production of cAMP. Amylin, amide, human (0.001 nM-1000 μM) results in an EC50 of 35.2±7.5 nM.
Amylin, amide, human, a 37-amino acid polypeptide, is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. Amylin, amide, human inhibits glucagon secretion, delays gastric emptying, and acts as a satiety agent.
体内研究：
Amylin, amide, human (400 μg peptide /kg body weight) is injected by subcutaneous route in separated groups of swiss male mice. A typical PK curve for the free amylin is observed, with a half-time of 23 min.Animal Model:Swiss male mice (8 weeks old)
Dosage:400 μg peptide /kg body weight (Pharmacokinetic Analysis)
Administration:Subcutaneous route; 24 hours
Result:Half-time of 23 min.
体外研究：
MCF-7 cells endogenously express human amylin receptor CTR1 and CTR2. Stimulation of the receptor with Amylin, amide, human results in the production of cAMP. Amylin, amide, human (0.001 nM-1000 μM) results in an EC50 of 35.2±7.5 nM.
产品资料
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