产品
编 号：F756987
分子式：C31H36ClN5O5S
分子量：626.17
分子式：C31H36ClN5O5S
分子量：626.17
产品类型
规格
价格
是否有货
10mM*1mL in DMSO
询价
询价
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2926716-96-1
产品详情
生物活性：
EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC50 values of 23.6 and 307.5 nM for EGFRLR/TM/CS and EGFRWT, respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research.
体外研究：
EGFR-IN-70 (compound 18j) (72 hours) has anti-proliferative activity and suppresses the proliferation of Ba/F3-EGFR19del/TM/CS, PC-9-OR-EGFR19del/TM/CS and A431- EGFRWT cells with IC50 values of 0.052, 0.644 and 2.003 μM, respectively.EGFR-IN-70 (compound 18j) (0-1000 nM; 2 hours; Ba/F3-EGFR19del/TM/CS and PC-9-OR-EGFR19del/TM/CS cells) can suppresse phosphorylation of the EGFR.
EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC50 values of 23.6 and 307.5 nM for EGFRLR/TM/CS and EGFRWT, respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research.
体外研究：
EGFR-IN-70 (compound 18j) (72 hours) has anti-proliferative activity and suppresses the proliferation of Ba/F3-EGFR19del/TM/CS, PC-9-OR-EGFR19del/TM/CS and A431- EGFRWT cells with IC50 values of 0.052, 0.644 and 2.003 μM, respectively.EGFR-IN-70 (compound 18j) (0-1000 nM; 2 hours; Ba/F3-EGFR19del/TM/CS and PC-9-OR-EGFR19del/TM/CS cells) can suppresse phosphorylation of the EGFR.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备