产品
编 号:F756890
分子式:C33H38N4O8
分子量:618.68
产品类型
结构图
CAS No: 2922280-86-0
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产品详情
生物活性:
MC3482 is a specific sirtuin5 (SIRT5) inhibitor.
体外研究:
MC3482 inhibits sirtuin5. 50 μM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-overexpressing cells.