产品
编 号:F756861
分子式:C18H16ClFN6
分子量:370.81
产品类型
结构图
CAS No: 2920000-86-6
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生物活性:
HPK1-IN-33 (compound 21) is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a Ki value of 1.7 nM. HPK1-IN-33 inhibits the produce of IL-2 with EC50s of 286, >10000 nM in Jurkat WT and Jurkat HPK1 KO cells, respectively.