产品
编 号:F756846
分子式:C21H16ClN3O4S
分子量:441.89
产品类型
结构图
CAS No: 2919216-33-2
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产品详情
生物活性:
CDK2-IN-9 is a potent CDK2 inhibitor with an IC50 of 0.63 μM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma.
体外研究:
CDK2-IN-9 (compound 5c) shows antiproliferative activity with IC50s of 3.03, 8.62, 62.52 μM for MDA-MB-435, SNB-75, WI-38 cells, respectively.CDK2-IN-9 (24 h) induces apoptosis and cell cycle arrest in S and G2/M phase.