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编 号:F756836
分子式:C29H31F3N6O4
分子量:584.59
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RET-IN-22 (compound 17b) is a?potent, selective and orally active RET inhibitor with an IC50 of 20.9 nM and 18.3 nM for wild-type RET and RET-V804M, respectively. RET-IN-22 shows highly selective profile to most kinases, especially to EGFR and VEGFR2. RET-IN-22 has anticancer effects.
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