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编 号:F756823
分子式:C20H22ClN3O2
分子量:371.86
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生物活性:
PARP-2-IN-2 (compound 27) is a PARP?2 inhibitor with an IC50 value of 0.057 μM. PARP-2-IN-2 induces cell cycle arrest and apoptosis of MCF-7 breast cancer cells. PARP-2-IN-2 can be used for the research of cancer.

体外研究:
PARP-2-IN-2 (0-1 μM; 1 h) inhibits PARP?2 with an IC50 value of 0.057 μM.PARP-2-IN-2 (0-100 μM; 24 h) shows cytotoxicity to MDA-MB-231 and MCF-7 cancer cells.PARP-2-IN-2 (16.7 μM; 24 h) induces cell cycle arrest and apoptosis.
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