产品
编 号：F756784
分子式：C26H27Cl2N7O2
分子量：540.44
分子式：C26H27Cl2N7O2
分子量：540.44
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CAS No: 2911640-63-4
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生物活性：
JNK3 inhibitor-5 (Compound 22b) is a potent and selective JNK3 inhibitor with an IC50 of 0.379 nM. JNK3 inhibitor-5 effectively protects the neuronal cells against amyloid beta-induced apoptosis. JNK3 inhibitor-5 has a high cell permeability and is predicted as BBB permeable.
体外研究：
JNK3 inhibitor-5 (Compound 22b) (10 μM; 24 h) 显示对淀粉样蛋白诱导的细胞凋亡有神经保护作用。
JNK3 inhibitor-5 (Compound 22b) is a potent and selective JNK3 inhibitor with an IC50 of 0.379 nM. JNK3 inhibitor-5 effectively protects the neuronal cells against amyloid beta-induced apoptosis. JNK3 inhibitor-5 has a high cell permeability and is predicted as BBB permeable.
体外研究：
JNK3 inhibitor-5 (Compound 22b) (10 μM; 24 h) 显示对淀粉样蛋白诱导的细胞凋亡有神经保护作用。
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