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编 号:F756751
分子式:C51H66N10O7S2
分子量:995.26
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10mM*1mL in DMSO
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1mg
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生物活性:
SNIPER(TACC3)-11 is a potent FGFR3-TACC3 degrader. SNIPER(TACC3)-11 reduces FGFR3-TACC3 protein levels and suppressed the growth of FGFR3-TACC3 positive cancer cells.

体外研究:
SNIPER(TACC3)-11 (compound 5a) (0.3-3 μM; 6 hours) reduces FGFR3-TACC3 levels.SNIPER(TACC3)-11 (0.3-3 μM; 72 hours) inhibits the growth of RT4 cells at 3 μM, and does not inhibit the growth of HeLa cells.
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