产品
编 号：F756726
分子式：C35H45ClN6O6S4
分子量：809.48
分子式：C35H45ClN6O6S4
分子量：809.48
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CAS No: 2901889-01-6
产品详情
生物活性：
ALK-IN-21 (Compound B10), a potent ALK inhibitor for ALKG1202R mutation, exhibits remarkable enzymatic inhibitory potency with IC50 values of 4.59 nM, 2.07 nM and 5.95 nM toward ALKWT, ALKL1196M and ALKG1202R, respectively. ALK-IN-21 efficiently inhibits the proliferation of ALK-positive Karpas299 and H2228 cells both with IC50 values of 0.07 μM. ALK-IN-21 can be used for the research of anaplastic large cell lymphoma.
体外研究：
ALK-IN-21 (Compound B10) inhibits the proliferation of Karpas299, H2228 and HCT116 cells with IC50 values of 0.07, 0.07 and 5.53 μM, respectively.
ALK-IN-21 (Compound B10), a potent ALK inhibitor for ALKG1202R mutation, exhibits remarkable enzymatic inhibitory potency with IC50 values of 4.59 nM, 2.07 nM and 5.95 nM toward ALKWT, ALKL1196M and ALKG1202R, respectively. ALK-IN-21 efficiently inhibits the proliferation of ALK-positive Karpas299 and H2228 cells both with IC50 values of 0.07 μM. ALK-IN-21 can be used for the research of anaplastic large cell lymphoma.
体外研究：
ALK-IN-21 (Compound B10) inhibits the proliferation of Karpas299, H2228 and HCT116 cells with IC50 values of 0.07, 0.07 and 5.53 μM, respectively.
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