产品
编 号:F756721
分子式:C21H24ClN7
分子量:409.92
产品类型
结构图
CAS No: 2901040-41-1
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产品详情
生物活性:
Chitinase-IN-4 (compound 8f), an azo-aminopyrimidine derivative, is a potent, selective OfChi-h inhibitor with an IC50 value of 0.1 μM. Chitinase-IN-4 has good insecticidal activity. Chitinase-IN-4 can be used in research of green pest control and management.
体外研究:
Chitinase-IN-4 (compound 8f; 0-1 μM) displays outstanding inhibitory potency via a benzyl on the amino group at the 4-position of pyrimidine, exhibits a Ki value of 64.7 nM against OfChi-h.Chitinase-IN-4 (100-500 μg/mL; 48 h) has insecticidal activity. Chitinase-IN-4 displays 100% mortality against P. xylostella at a concentration of 500 μg/mL, which is much higher than that of the control drug hexaflumuron, and inhibits 22.5% Ostrinia nubilalis at a concentration of 500 μg/mL.