产品
编 号：F756710
分子式：C22H19N3O3
分子量：373.4
分子式：C22H19N3O3
分子量：373.4
产品类型
规格
价格
是否有货
结构图
CAS No: 2897622-19-2
产品详情
生物活性：
PIM-1/HDAC-IN-1 (compound 4d) is a PIM-1 inhibitor, with an IC50 of 343.87 nM. PIM-1/HDAC-IN-1 has strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC50 values of 63.65 and 62.39 nM, respectively. PIM-1/HDAC-IN-1 exhibits apoptosis inducing potential in MCF-7 cell lines. PIM-1/HDAC-IN-1 shows pre-G1 apoptosis and cell cycle arrest at G2/M phase.
体外研究：
PIM-1/HDAC-IN-1 (compound 4d) displays strong antiproliferative activity against cancer cell lines, with GI50 (growth inhibitory activity) ≤ 3 μM (GI50 range from 0.325 to 2.9 μM).
PIM-1/HDAC-IN-1 (compound 4d) is a PIM-1 inhibitor, with an IC50 of 343.87 nM. PIM-1/HDAC-IN-1 has strong inhibitory activity and selectivity against HDAC 1 and HDAC 6, with IC50 values of 63.65 and 62.39 nM, respectively. PIM-1/HDAC-IN-1 exhibits apoptosis inducing potential in MCF-7 cell lines. PIM-1/HDAC-IN-1 shows pre-G1 apoptosis and cell cycle arrest at G2/M phase.
体外研究：
PIM-1/HDAC-IN-1 (compound 4d) displays strong antiproliferative activity against cancer cell lines, with GI50 (growth inhibitory activity) ≤ 3 μM (GI50 range from 0.325 to 2.9 μM).
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