产品
编 号：F756660
分子式：C44H35NO6
分子量：673.75
分子式：C44H35NO6
分子量：673.75
产品类型
规格
价格
是否有货
结构图
CAS No: 2891831-47-1
产品详情
生物活性：
PD-1/PD-L1-IN-27 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 134 nM. PD-1/PD-L1-IN-27 shows antitumor effects with low T cell cytotoxicity. PD-1/PD-L1-IN-27 has the ability to activate CD8+ T cells and reduces T cell exhaustion.
体内研究：
PD-1/PD-L1-IN-27 (10, 25 mg/kg; i.g.) shows antitumor effecct.Animal Model:20-22 g, 6-8 weeks, male C57BL/6J mice (MC 38 cell lines)
Dosage:10, 25 mg/kg
Administration:I.g.
Result:Showed antitumor effecct.
体外研究：
PD-1/PD-L1-IN-27 (compound MZ58) (2.5, 5, 10, 50 μM; 48 h) shows antitumor effects with low T cell cytotoxicity.
PD-1/PD-L1-IN-27 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 134 nM. PD-1/PD-L1-IN-27 shows antitumor effects with low T cell cytotoxicity. PD-1/PD-L1-IN-27 has the ability to activate CD8+ T cells and reduces T cell exhaustion.
体内研究：
PD-1/PD-L1-IN-27 (10, 25 mg/kg; i.g.) shows antitumor effecct.Animal Model:20-22 g, 6-8 weeks, male C57BL/6J mice (MC 38 cell lines)
Dosage:10, 25 mg/kg
Administration:I.g.
Result:Showed antitumor effecct.
体外研究：
PD-1/PD-L1-IN-27 (compound MZ58) (2.5, 5, 10, 50 μM; 48 h) shows antitumor effects with low T cell cytotoxicity.
产品资料
Copyright©2015-2024 沪ICP备2022026524号-1
沪公网安备