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编 号:F756634
分子式:C16H16Cl2FNO2
分子量:344.21
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生物活性:
Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads.

体外研究:
Phosphatase-IN-1 (compound II-8) 在 223 60 μM 浓度下可有效抑制八种植物病原体的营养生长。与野生菌株相比,Phosphatase-IN-1 (compound II-8) 对 Mopah1 突变体的抑制作用减弱。
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