产品
编 号：F756611
分子式：C21H18O5
分子量：350.36
分子式：C21H18O5
分子量：350.36
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CAS No: 2883506-60-1
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生物活性：
Nrf2/HO-1 activator 1 (Compound 24) is a potent Nrf2/HO-1 activator, neuroprotective agent. Nrf2/HO-1 activator 1 shows neuroprotective and antioxidant activities. Nrf2/HO-1 activator 1 can be used in Parkinson's disease (PD) research.
体内研究：
Nrf2/HO-1 activator 1 inhibits the production of lipid peroxide in rat brain homogenates by 50.5% at 100 μM.
体外研究：
Nrf2/HO-1 activator 1 (0.3-30 μM; 24 h) exhibits potent neuroprotection in both 6-OHDA- and rotenone-induced cell death models.Nrf2/HO-1 activator 1 (1-30 μM; 6 h) increases HO-1 expression in PC12 cells.Nrf2/HO-1 activator 1 (12 μM; 1-12 h) increases phosphorylation of ERK1/2, JNK, and Akt in PC12 cells.
Nrf2/HO-1 activator 1 (Compound 24) is a potent Nrf2/HO-1 activator, neuroprotective agent. Nrf2/HO-1 activator 1 shows neuroprotective and antioxidant activities. Nrf2/HO-1 activator 1 can be used in Parkinson's disease (PD) research.
体内研究：
Nrf2/HO-1 activator 1 inhibits the production of lipid peroxide in rat brain homogenates by 50.5% at 100 μM.
体外研究：
Nrf2/HO-1 activator 1 (0.3-30 μM; 24 h) exhibits potent neuroprotection in both 6-OHDA- and rotenone-induced cell death models.Nrf2/HO-1 activator 1 (1-30 μM; 6 h) increases HO-1 expression in PC12 cells.Nrf2/HO-1 activator 1 (12 μM; 1-12 h) increases phosphorylation of ERK1/2, JNK, and Akt in PC12 cells.
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