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编 号:F756601
分子式:C28H26O4
分子量:426.5
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生物活性:
TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor.

体外研究:
TMV-IN-1 (compound N2) 对 TMV 具有良好的处理活性和保护活性,EC50 值分别为 70.7 μg/mL 和 60.8 μg/mL.TMV-IN-1 可结合 TMV 外壳蛋白 (TMV-CP),Kd 值为 0.0427 μM。TMV-IN-1 (5-7days) 降低丙二醛的增加速率,增加防御酶的含量。
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