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编 号:F756587
分子式:C19H14N4O2S
分子量:362.41
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生物活性:
Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis.

体外研究:
Antitubercular agent 34 (0-20 μg/mL; 3-4 d) shows inhibitory effect to MtbH37Rv with a MIC90 value of 1.25 μg/mL.Antitubercular agent 34 (0-100 μM; 3 d) shows inhibitory effect to human monocytes THP-I cell line.
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