产品
编 号：F756533
分子式：C27H28N2O6
分子量：476.52
分子式：C27H28N2O6
分子量：476.52
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CAS No: 2874264-13-6
产品详情
生物活性：
VEGFR-IN-3 (compound 3f) is a VEGFR inhibitor. VEGFR-IN-3 inhibits OVCAR-4 and MDA-MB-468 cancer cells growth with IC50s of 0.29 and 0.35 μM, respectively. VEGFR-IN-3 can be used for the research of cancer.
体外研究：
VEGFR-IN-3 (10 μM; 60 min) inhibits a variety of cancer cell lines growth.VEGFR-IN-3 (0-100 μM; 72 h) shows cytotoxic activities against MDA-MB-468 and OVCAR-4 cancer cell lines.VEGFR-IN-3 (0.29-0.35 μM; 2.5 h) decreases the concentration of VEGF in OVCAR-4 and MDA-MB-468 cell lines.VEGFR-IN-3 (0.29 μM; 48 h) increases levels of ERK1 and ERK2, activates ERK1 and ERK2 phosphorylation.VEGFR-IN-3 (0.29 μM; 24 h) affects cell cycle and induces apoptosis of OVCAR-4 cancer cells.
VEGFR-IN-3 (compound 3f) is a VEGFR inhibitor. VEGFR-IN-3 inhibits OVCAR-4 and MDA-MB-468 cancer cells growth with IC50s of 0.29 and 0.35 μM, respectively. VEGFR-IN-3 can be used for the research of cancer.
体外研究：
VEGFR-IN-3 (10 μM; 60 min) inhibits a variety of cancer cell lines growth.VEGFR-IN-3 (0-100 μM; 72 h) shows cytotoxic activities against MDA-MB-468 and OVCAR-4 cancer cell lines.VEGFR-IN-3 (0.29-0.35 μM; 2.5 h) decreases the concentration of VEGF in OVCAR-4 and MDA-MB-468 cell lines.VEGFR-IN-3 (0.29 μM; 48 h) increases levels of ERK1 and ERK2, activates ERK1 and ERK2 phosphorylation.VEGFR-IN-3 (0.29 μM; 24 h) affects cell cycle and induces apoptosis of OVCAR-4 cancer cells.
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