产品
编 号：F756468
分子式：C17H11Cl2F3N2O3S
分子量：451.25
分子式：C17H11Cl2F3N2O3S
分子量：451.25
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结构图
CAS No: 2866499-55-8
产品详情
生物活性：
Cas9-IN-1 is a potent Cas9 inhibitor (IC50=7.02 μM), acting by binding to apo-Cas9 to prevent Cas9:gRNA complex formation.
体外研究：
Cas9-IN-1 (compound 85) (5 and 13 μM; overnight) can detach gRNA from preformed Cas9:gRNA complex while having weaker inhibitory activity, helping the E. coli selection strain to survive SpyCas9-induced killing.
Cas9-IN-1 is a potent Cas9 inhibitor (IC50=7.02 μM), acting by binding to apo-Cas9 to prevent Cas9:gRNA complex formation.
体外研究：
Cas9-IN-1 (compound 85) (5 and 13 μM; overnight) can detach gRNA from preformed Cas9:gRNA complex while having weaker inhibitory activity, helping the E. coli selection strain to survive SpyCas9-induced killing.
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