产品
编 号：F756401
分子式：C20H21N5
分子量：331.41
分子式：C20H21N5
分子量：331.41
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2857982-26-2
产品详情
生物活性：
PIKfyve-IN-1 is a highly potent and cell-active chemical probe that inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) with IC50 value of 6.9 nM. PIKfyve-IN-1 can be used for the research of PIKfyve in virology. PIKfyve-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
PIKfyve-IN-1 inhibits PIKfyve in PIKfyve enzymatic assay and PIKfyve NanoBRET assay with IC50 values of 6.9 nM and 4.01 nM, respectively. PIKfyve-IN-1 (0-10 μM) disrupts multiple phases of the lifecycle of coronaviruses: viral replication and viral entry. PIKfyve-IN-1 inhibits MHV replication and SARS-CoV-2 replication with IC50 values of 23.5 nM and 19.5 nM, respectively.PIKfyve-IN-1 (5 μM) impacts lysosomal homeostasis.
PIKfyve-IN-1 is a highly potent and cell-active chemical probe that inhibits phosphatidylinositol-3phosphate 5-kinase (PIKfyve) with IC50 value of 6.9 nM. PIKfyve-IN-1 can be used for the research of PIKfyve in virology. PIKfyve-IN-1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
体外研究：
PIKfyve-IN-1 inhibits PIKfyve in PIKfyve enzymatic assay and PIKfyve NanoBRET assay with IC50 values of 6.9 nM and 4.01 nM, respectively. PIKfyve-IN-1 (0-10 μM) disrupts multiple phases of the lifecycle of coronaviruses: viral replication and viral entry. PIKfyve-IN-1 inhibits MHV replication and SARS-CoV-2 replication with IC50 values of 23.5 nM and 19.5 nM, respectively.PIKfyve-IN-1 (5 μM) impacts lysosomal homeostasis.
产品资料
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