产品
编 号：F756359
分子式：C17H14ClN3OS
分子量：343.83
分子式：C17H14ClN3OS
分子量：343.83
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CAS No: 2851067-08-6
产品详情
生物活性：
PI3K/VEGFR2-IN-1 is a potent dual PI3K/VEGFR2 inhibitor with IC50 values of 2.21 and 68 μM for PI3K and VEGFR2, respectively. PI3K/VEGFR2-IN-1 induces apoptosis. PI3K/VEGFR2-IN-1 can be used in research of cancer.
体外研究：
PI3K/VEGFR2-IN-1 (compound 8; 1.56-100 μM; 24 h; HePG2, MCF-7, Hela, and PC3 cells) inhibits cell proliferative in a dose-dependent manner.PI3K/VEGFR2-IN-1 (10 mg/mL; 24 h; MCF-7 and Hela cells) arrests cell cycle at G1/S phase and induces apoptosis.
PI3K/VEGFR2-IN-1 is a potent dual PI3K/VEGFR2 inhibitor with IC50 values of 2.21 and 68 μM for PI3K and VEGFR2, respectively. PI3K/VEGFR2-IN-1 induces apoptosis. PI3K/VEGFR2-IN-1 can be used in research of cancer.
体外研究：
PI3K/VEGFR2-IN-1 (compound 8; 1.56-100 μM; 24 h; HePG2, MCF-7, Hela, and PC3 cells) inhibits cell proliferative in a dose-dependent manner.PI3K/VEGFR2-IN-1 (10 mg/mL; 24 h; MCF-7 and Hela cells) arrests cell cycle at G1/S phase and induces apoptosis.
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