产品
编 号：F756349
分子式：C20H20N8O2S
分子量：436.49
分子式：C20H20N8O2S
分子量：436.49
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CAS No: 2849348-38-3
产品详情
生物活性：
hCAIX-IN-16 (Compound 12d) is hCA IX inhibitor, with Ki
体外研究：
hCAIX-IN-16 (3.99 μM; 24 h) arrests cell growth in G0-G1 and S phases in MDA-MB-468 cells.hCAIX-IN-16 (10 μM) inhibits the growth of 44 cancer cell lines with GI% ≥ 10% and shows GI% ≥ 50% against leukemia, (CCRF-CEM, RPMI-8226 and SR) and breast cancer cell lines (T-47D and MDA-MB-468).hCAIX-IN-16 induces cell death by the apoptotic mechanism in MDA?MB?468 cells.Inhibits (under hypoxic conditions) MDA-MB-468 and CCRF-CM cells with IC50s of 3.99 and 4.51 μM, respectively.
hCAIX-IN-16 (Compound 12d) is hCA IX inhibitor, with Ki
体外研究：
hCAIX-IN-16 (3.99 μM; 24 h) arrests cell growth in G0-G1 and S phases in MDA-MB-468 cells.hCAIX-IN-16 (10 μM) inhibits the growth of 44 cancer cell lines with GI% ≥ 10% and shows GI% ≥ 50% against leukemia, (CCRF-CEM, RPMI-8226 and SR) and breast cancer cell lines (T-47D and MDA-MB-468).hCAIX-IN-16 induces cell death by the apoptotic mechanism in MDA?MB?468 cells.Inhibits (under hypoxic conditions) MDA-MB-468 and CCRF-CM cells with IC50s of 3.99 and 4.51 μM, respectively.
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