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编 号：F756337
分子式：C26H19N3O4S
分子量：469.51
分子式：C26H19N3O4S
分子量：469.51
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CAS No: 2848581-84-8
产品详情
生物活性：
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research.
体内研究：
PTP1B-IN-18 (Compound 44; 100 mg/kg; p.o.; single administration) reduces 23% of the blood sugar level.Animal Model:Female Wistar rats weighing 200-250 g (type 2 diabetic rat model)
Dosage:100 mg/kg
Administration:Oral administration; single administration
Result:Showed hypoglycemic effect under physiological conditions.
PTP1B-IN-18 is an orally active complete mixed type protein tyrosine phosphatase 1B (PTP1B) inhibitor with a Ki of 35.2 μM. PTP1B-IN-18 can be used for type 2 diabetes research.
体内研究：
PTP1B-IN-18 (Compound 44; 100 mg/kg; p.o.; single administration) reduces 23% of the blood sugar level.Animal Model:Female Wistar rats weighing 200-250 g (type 2 diabetic rat model)
Dosage:100 mg/kg
Administration:Oral administration; single administration
Result:Showed hypoglycemic effect under physiological conditions.
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