产品
编 号：F756291
分子式：C50H53F3N8O9
分子量：967
分子式：C50H53F3N8O9
分子量：967
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规格
价格
是否有货
结构图
CAS No: 2839318-19-1
产品详情
生物活性：
dBRD4-BD1 is a selective and durable BRD4 degrader with an DC50 value of 280 nM (Dmax=77%). dBRD4-BD1 upregulates BRD2/3 protein level and shows low cytotoxicity than iBRD4-BD1.
体外研究：
dBRD4-BD1 (64 pM-25 nM; 24 h) degrades BDR4 in a dose-dependent manner.dBRD4-BD1 (5 μM; 0-72 h) increases the protein level of BRD2 and BRD3.
dBRD4-BD1 is a selective and durable BRD4 degrader with an DC50 value of 280 nM (Dmax=77%). dBRD4-BD1 upregulates BRD2/3 protein level and shows low cytotoxicity than iBRD4-BD1.
体外研究：
dBRD4-BD1 (64 pM-25 nM; 24 h) degrades BDR4 in a dose-dependent manner.dBRD4-BD1 (5 μM; 0-72 h) increases the protein level of BRD2 and BRD3.
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