产品
编 号：F756284
分子式：C17H16N2O
分子量：264.32
分子式：C17H16N2O
分子量：264.32
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CAS No: 2839151-13-0
产品详情
生物活性：
Tubulin inhibitor 17 (Compound 3b) is a tubulin polymerization inhibitor with an IC50 of 12.38 μM. Tubulin inhibitor 17 has anticancer activities and induces cell apoptosis.
体外研究：
Tubulin inhibitor 17 (Compound 3b) (0-10 μM, 0-72 h) displays antiproliferative activities against cancer cells and inhibits colony formation of HepG-2 cells.Tubulin inhibitor 17 (0-2.5 μM) inhibits tubulin polymerization in a concentration-dependent manner.Tubulin inhibitor 17 (0-1 μM, 12 h) induces the collapse of the microtubule networks in a dose-dependent manner.Tubulin inhibitor 17 (0-5 μM, 24 h) induces cell cycle arrest at G2/M phase and inhibits cell migration in HepG-2 cells.Tubulin inhibitor 17 (0-5 μM, 48 h) induces HepG-2 cell apoptosis.
Tubulin inhibitor 17 (Compound 3b) is a tubulin polymerization inhibitor with an IC50 of 12.38 μM. Tubulin inhibitor 17 has anticancer activities and induces cell apoptosis.
体外研究：
Tubulin inhibitor 17 (Compound 3b) (0-10 μM, 0-72 h) displays antiproliferative activities against cancer cells and inhibits colony formation of HepG-2 cells.Tubulin inhibitor 17 (0-2.5 μM) inhibits tubulin polymerization in a concentration-dependent manner.Tubulin inhibitor 17 (0-1 μM, 12 h) induces the collapse of the microtubule networks in a dose-dependent manner.Tubulin inhibitor 17 (0-5 μM, 24 h) induces cell cycle arrest at G2/M phase and inhibits cell migration in HepG-2 cells.Tubulin inhibitor 17 (0-5 μM, 48 h) induces HepG-2 cell apoptosis.
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