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编 号:F756254
分子式:C7H10N2S2
分子量:186.3
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生物活性:
Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity.

体内研究:
Antifungal agent 37 (200 μg/mL; sprinkling; for 14 d) inhibits rice bacterial blight in vivo.

体外研究:
Antifungal agent 37 (50 μg/mL) shows anti-fungal activity against 10 pathogenic fungi with inhibition rates of 65.46% (R. solani), 98.56% (S. sclerotiorum), 41.99% (B. cinerea), 66.80% (F. graminearum), 36.70% (M. oryzae), 28.26% (P. capsici), 100% (A. flavus), 57.35% (P. expansum), 89.64% (M. fructicola), 59.03% (R. stolonifer), respectively.Antifungal agent 37 inhibits fungus growth with EC50s of 10.67 μg/mL (R. solani), 10.10 μg/mL (S. sclerotiorum), 23.49 μg/mL (F. graminearum), >10 μg/mL (A. flavus), 9.71 μg/mL (M. fructicola), 21.54 μg/mL (R. stolonifer), respectively.Antifungal agent 37 shows an excellent antibacterial effect on X. oryzae, with an MIC value of 1.56 μg/mL, which was better than the positive control drug TC.
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