产品
编 号：F756221
分子式：C16H7ClF2N2O
分子量：316.69
分子式：C16H7ClF2N2O
分子量：316.69
产品类型
规格
价格
是否有货
1mg
询价
询价
5mg
询价
询价
10mg
询价
询价
结构图
CAS No: 2829349-96-2
产品详情
生物活性：
FTX-6746 is an orally active PPARG inhibitor. FTX-6746 shows potent tumor inhibition in mouse xenograft models.
体内研究：
FTX-6746 (3-60 mg/kg；口服；每天 2 次，共 21 天) 在小鼠的 UMUC9 或 HT1197 异种移植模型中有显着的肿瘤抑制作用。Animal Model:UMUC9 or HT1197 xenograft model in NCG or Balb/C nude mice
Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg, 60 mg/kg
Administration:PO; twice daily for 21 days
Result:Resulted >100% tumor growth inhibition at day 21 in HT1197 xenograft model. Resulted up to 80% target gene suppression in tumor tissue at day 2.
FTX-6746 is an orally active PPARG inhibitor. FTX-6746 shows potent tumor inhibition in mouse xenograft models.
体内研究：
FTX-6746 (3-60 mg/kg；口服；每天 2 次，共 21 天) 在小鼠的 UMUC9 或 HT1197 异种移植模型中有显着的肿瘤抑制作用。Animal Model:UMUC9 or HT1197 xenograft model in NCG or Balb/C nude mice
Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg, 60 mg/kg
Administration:PO; twice daily for 21 days
Result:Resulted >100% tumor growth inhibition at day 21 in HT1197 xenograft model. Resulted up to 80% target gene suppression in tumor tissue at day 2.
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