产品
编 号：F756192
分子式：C26H36N6O3
分子量：480.6
分子式：C26H36N6O3
分子量：480.6
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规格
价格
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结构图
CAS No: 2824922-28-1
产品详情
生物活性：
BTK-IN-8 is a potent and selective peripheral covalent BTK inhibitor (IC50=0.22 nM; Kd=0.91 nM). BTK-IN-8 has good whole blood CD69 cellular potency (IC50=0.029 μM).
体外研究：
BTK-IN-8 (compound 42) shows potent target occupancy in Ramos cells (IC50=3.1 nM) and inhibits BTK-dependent TMD8 cells proliferation (IC50= 1.6 nM).
BTK-IN-8 is a potent and selective peripheral covalent BTK inhibitor (IC50=0.22 nM; Kd=0.91 nM). BTK-IN-8 has good whole blood CD69 cellular potency (IC50=0.029 μM).
体外研究：
BTK-IN-8 (compound 42) shows potent target occupancy in Ramos cells (IC50=3.1 nM) and inhibits BTK-dependent TMD8 cells proliferation (IC50= 1.6 nM).
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