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编 号:F756171
分子式:C9H8BrF2N
分子量:248.07
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生物活性:
LSD1/2-IN-4, a PCPA derivative, is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2). LSD1/2-IN-4 inhibits LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively. LSD1/2-IN-4 can be used for the research of several cancers including T-cell acute lymphoblastic leukemia (TALL).

体外研究:
LSD1/2-IN-4 shows strong inhibitory activity against both LSD1 and LSD2 with Ki values of 0.11 μM and 130 μM, respectively and not inhibits peroxidase with an IC50 >500 μM.
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