产品
编 号：F756151
分子式：C19H21N3O2S
分子量：355.45
分子式：C19H21N3O2S
分子量：355.45
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CAS No: 2820126-28-9
产品详情
生物活性：
EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR/HER2 kinase and DHFR inhibitor, with IC50s of 0.18 μM (EGFR), 0.146 μM (HER2), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR (IC50=0.907 μM).
体外研究：
EGFR/HER2-IN-7 (compound 27) shows remarkable broad spectrum cytotoxic potency, with an IC50 value of 10.81 μM against MCF-7 breast cancer cells. EGFR/HER2-IN-7 (72 h) displays anti-breast cancer activity with an IC50 value of 8.29 μM.
EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR/HER2 kinase and DHFR inhibitor, with IC50s of 0.18 μM (EGFR), 0.146 μM (HER2), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR (IC50=0.907 μM).
体外研究：
EGFR/HER2-IN-7 (compound 27) shows remarkable broad spectrum cytotoxic potency, with an IC50 value of 10.81 μM against MCF-7 breast cancer cells. EGFR/HER2-IN-7 (72 h) displays anti-breast cancer activity with an IC50 value of 8.29 μM.
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