产品
编 号：F756108
分子式：C26H30ClN5O
分子量：464
分子式：C26H30ClN5O
分子量：464
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规格
价格
是否有货
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CAS No: 2813347-44-1
产品详情
生物活性：
ZLWT-37 is a potent, orally active CDKs inhibitor with IC50 values of 0.002 μM and 0.054 μM against CDK9 and CDK2, respectively. ZLWT-37 induces apoptosis and arrests the cell cycle in the G2/M phase in HCT116 cells.
体内研究：
ZLWT-37 (0-20 mg/kg; p.o.; once daily for 14 consecutive days) shows potential efficacy against the growth of implanted HCT116 cells in mice without obvious toxicity.
体外研究：
ZLWT-37 shows antiproliferative activity with a GI50 of 0.029 μM for HCT116.
ZLWT-37 is a potent, orally active CDKs inhibitor with IC50 values of 0.002 μM and 0.054 μM against CDK9 and CDK2, respectively. ZLWT-37 induces apoptosis and arrests the cell cycle in the G2/M phase in HCT116 cells.
体内研究：
ZLWT-37 (0-20 mg/kg; p.o.; once daily for 14 consecutive days) shows potential efficacy against the growth of implanted HCT116 cells in mice without obvious toxicity.
体外研究：
ZLWT-37 shows antiproliferative activity with a GI50 of 0.029 μM for HCT116.
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