产品
编 号:F756107
分子式:C37H33F3N6O7PtS2
分子量:989.9
产品类型
结构图
CAS No: 2813334-66-4
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产品详情
生物活性:
hCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer.
体外研究:
hCAIX-IN-13 (10 and 20 μM; 24 h) effectively attenuates extracellular acidification through the inhibited activity of the cellular CAIX expression.hCAIX-IN-13 (20 and 40 μM; 24 h) affects CAIX expression.hCAIX-IN-13 (0-200 μM; 24 h) shows high cytotoxicity to cancer cell lines.hCAIX-IN-13 (5-15 μM; 24 h) promotes the production of cellular ROS.hCAIX-IN-13 (5-20 μM; 48 h) induces cell apoptosis.