产品
编 号:F756061
分子式:C21H28ClN3O2
分子量:389.92
产品类型
结构图
CAS No: 2803211-60-9
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产品详情
生物活性:
GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein.
体外研究:
GRP-60367 (0.1 nM-1000 μM) confirms specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52?nM on different host cell lines.