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编 号:F756053
分子式:C35H54BNO6
分子量:595.62
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生物活性:
Autotaxin-IN-6 (compound 23) is a potent autotaxin (ATX) inhibitor with an IC50 value of 30 nM. Autotaxin-IN-6 can reduce cell migration. Autotaxin-IN-6 can be used for researching anticancer.

体外研究:
Autotaxin-IN-6 (compound 23) inhibits ATX-stimulated HeLa cells and results in significantly decrease of LPA1 internalization of approximately 75%.Autotaxin-IN-6 prevents LPA1 activation and its Gαi- and PI3K-dependent signaling responses.
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