产品
编 号:F756044
分子式:C20H17Cl2F3N4O4
分子量:505.27
产品类型
结构图
CAS No: 2797619-81-7
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产品详情
生物活性:
FTO-IN-1 TFA is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 TFA can be used for the research of cancer.
体外研究:
FTO-IN-1 TFA (50 μM) inhibits FTO enzyme activity by 62% in vitro.FTO-IN-1 TFA (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively.