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编 号:F756041
分子式:C24H25Cl2N5OS
分子量:502.46
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生物活性:
PfGSK3/PfPK6-IN-2 is a potent dual PfGSK3/PfPK6 (Plasmodium falciparum GSK3/PK6) inhibitor (IC50: 172 nM and 11 nM respectively). PfGSK3/PfPK6-IN-2 can be used in the research of Malaria.

体外研究:
PfGSK3/PfPK6-IN-2 (compound 23d) inhibits P. falciparum 3D7 load in erythrocytes (EC50: 552 nM).PfGSK3/PfPK6-IN-2 (2 μM) shows cytotoxicity against HepG2 cells.
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