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编 号:F756037
分子式:C10H13BN2O4
分子量:236.03
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生物活性:
MRV03-070 is an inhibitor of colibactin-activating peptidase ClbP with an IC50 value of 69 nM, acts like biosynthetic precursor precolibactin.

体外研究:
MRV03-070 (compound 4) (0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity with IC50s of 69 nM and 27 nM, respectively, measured both in vitro and in E. coli BL21 overexpressing ClbP.
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