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编 号:F756036
分子式:C9H19BN2O4
分子量:230.07
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生物活性:
MRV03-037 is a selective colibactin-activated peptidase (ClbP) inhibitor that blocks the genotoxic effect of Colibactin (HY-145930) on eukaryotic cells. MRV03-037 prevents gut bacterial genotoxin production.

体外研究:
MRV03-037 (compound 1; 0.01 nM-0.1 mM for 1 h) inhibits ClbP acitivity in E. coli BL21 overexpressing ClbP.
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