产品
编 号:F756017
分子式:C41H46N12O5S
分子量:818.95
产品类型
结构图
CAS No: 2789678-92-6
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生物活性:
SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.