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编 号:F756004
分子式:C50H70N10O16
分子量:1067.15
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生物活性:
TP0556351 is a potent and selective matrix metalloproteinase-2 (MMP2) inhibitor with an IC50 value of 0.2 nM. TP0556351 reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model. TP0556351 can be used for researching idiopathic pulmonary fibrosis (IPF).

体内研究:
TP0556351 (0.03, 0.1, 0.3, or 1 mg/kg/day; SC, for 14 days) reduces the amount of collagen in the lungs of a Bleomycin-induced pulmonary fibrosis mouse model.
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